TY - BOOK AU - Nóbrega,Clévio AU - Mendonça,Liliana AU - Matos,Carlos A. ED - SpringerLink (Online service) TI - A Handbook of Gene and Cell Therapy SN - 9783030413330 AV - RB155-155.8 U1 - 611.01816 23 PY - 2020/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Medical genetics KW - Gene therapy KW - Gene expression KW - Animal genetics KW - Gene Function KW - Gene Therapy KW - Gene Expression KW - Animal Genetics and Genomics N1 - 1. Gene and Cell therapy overview -- 2. Gene and Cell therapy history -- 3. Delivery systems for gene therapy -- 4. Stem-cells and tissue regeneration theories -- 5. Gene therapy strategies -- 6. Gene and cell therapy applications -- 7. Gene therapy clinical trials -- 8. Research in gene therapy: celllular and animal models -- 9. Future challenges in gene and cell therapy N2 - This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field UR - https://doi.org/10.1007/978-3-030-41333-0 ER -